SEROLOGIC RESPONSE TO STREPTOCOCCAL HEMOLYSIN AND HYALURONIDASE IN STREPTOCOCCAL AND RHEUMATIC INFECTION
نویسندگان
چکیده
منابع مشابه
Serologic Response to Streptococcal Hemolysin and Hyaluronidase in Streptococcal and Rheumatic Infection.
Although it has as yet not been possible to demonstrate the specific role of a causative organism in rheumatic fever, there has been considerable epidemiologic (1) and serologic (2) evidence of some relationship between the hemolytic streptococcus and this disease. Studies of both cellular and extracellular substances of the hemolytic streptococcus have with rare exceptions shown that groups of...
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Objective(s): Streptococcus pyogenes produces extracellular hyaluronidase enzyme. This enzyme is directly associated with the spread of the organism during infection. The objective of the present study was to clone and express the nucleotide sequence of the enzyme which is involved in hyaluronidase enzymatic activity. Materials and Methods: The enzymatic region of hyaluronidase gene was detecte...
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The atiology of rheumatism has engaged the attention of bacteriologists for many years, and yet it is impossible to say that any definite conclusion has been reached. Many authors have suggested various types of non-haemolytic streptococci as possible causes, but none of their claims has been definitely established, and the vast amount of literature that has accumulated does not bring us much n...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1950
ISSN: 0021-9738
DOI: 10.1172/jci102265